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Indian Definition of AIDS

National AIDS Organization concept of AIDS in adults in India is defined as who has

Positive test of HIV antibodies detected by the separate tests using two different antigens, and any one of the following criterion;

1. (a) weight lost of 10% or Pyrexia
1. (b) Chronic diarrhea of one month duration of chronic cough, one month duration.
2. Disseminated pulmonary or extra-pulmonary tuberculosis
3. Neurological impairment restricting daily activities
4. Candidiasis of the esophagus diagnosable, dysphaxia (odynophagia) along with the oral Candidiasis
5. D. Sarcoma.

Clinical stage progression is as follows :

Stage I : HIV infection - Asymptomatic

Stage II : HIV related disease - Symptomatic
Pulmonary tuberculosis, Thrombocytopenia
Stage III : Advanced HIV/AIDS

A person with AIDS Related Complex has illness caused by damage to the immune system, but without opportunistic infections and cancers associated with AIDS, but they exhibit one or more of the following signs.

i. Un-explained diarrhea, lasting longer than a month
ii. Fatigue
iii. Malaria
iv. Loss of more than 10% body weight
v. Fever
vi. Night sweats, or other milder opportunistic infections such as oral thrust, generalized Lymphadenopathy, enlarged spleen

Normally people with healthy immune system have more than 950 T-Helper cells in each Cu.mm of blood, although a few people do not have more than 500 and remain healthy. The number of T-Helper cells usually falls over course of HIV infection. People with AIDS usually have T-Helper cell counts below 200. AIDS is the ending stage of HIV infection. The average survival time after AIDS diagnosis is 1-3 year and this may be influenced by exposure to opportunistic infection or access to health care.

International Definition of AIDS

The Center of Disease Control devised an AIDS case definition and classification system base on presence of certain opportunistic infection and / or malignancies in the absence of other causes of immuno-deficiencies. The average survival time after diagnosis is 1-3 year. This may be influence by exposure of opportunistic infection access to health care.

A1 - 500 CD4

Asymptomatic

B1 - 500 CD4

Cut Loss

Pyrexia
C1 - 500 CD4

CD4 10% lost,

Wt loss, no pyrexia

C T.B. infection
A2 – 499 CD4

Asymptomatic
B2 - 499 CD4

Wt. Loss

Pyrexia
C2 - 499 CD4

CD4 10% wt. Loss.

High grade continuous fever C T.B. infection
A3 200 CD4

Asymptomatic
B3 - 200 CD4

Wt. Loss

Pyrexia
C3 - 200 CD4

10% wt loss 

T.B. infection
C3 grade patience will combact in A1 Catogory.

1993 Revised Classification system for HIV Infection and Expanded AIDS Surveillance Case Definition for Adolescents and Adults.

Clinical Categories
CD4+T -cell

Category
(A) ASYMPTOMATIC ACCUTE (primary) HIV or PGL (B) Symptomatic, Not (A) or (C) Conditions (C) AIDS – indicator Conditions
(1) > 500/mm3 A1 B1 C1
(2) 200-499/ mm3 A2 B2 C2
(3) <200/ mm3

(AIDS indicator T-cell count)
A3 B3 C3

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